More than a decade has passed since the completion of the Human Genome Project, the international collaboration to map all of the "letters" in our DNA. The huge effort led to revolutionary genomic discoveries, but more than 10 years later, it's still unclear what percentage of the human genome is actually doing something important.
A new study suggests that only 8.2% of human DNA, or about 250 million of these so-called DNA letters, are functional, and more than two billion are not.
The results are higher than previous estimates of 3% to 5%, and significantly lower than the 80% reported in 2012 by the Encyclopedia of DNA Elements Project (ENCODE) , a public research project led by the U.S. National Human Genome Research Institute to study the role of the three billion total letters in human DNA. Read more...
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